About Us
Equity through innovation
The NIHR Biomedical Research Centre: Moorfields (BRC) is part of the NIHR. We are a partnership between Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology.
We are dedicated to pioneering research that transforms the lives of patients facing sight loss. Our vision is to change lives across the UK and the world by preserving sight and driving equity through innovation, particularly for those with the greatest need.
We are the only BRC dedicated to eye health research. Since 2007, we have been pioneering the translation of laboratory discoveries into treatments for the benefit of patients with eye conditions and for the NHS. Our university-hospital partnership is ranked number one in the world for ophthalmology research (Center for World University Rankings 2017).
Our aims
The aims of our BRC cover five areas:
We aim to maximise our impact on eye health by targeting common and rare eye conditions that lead to life-long visual impairment in young people. This will help tackle the lack of opportunities that can affect people with sight-loss throughout their lives.
We aim to develop new ways of identifying those at risk of vision loss, enabling earlier preventative treatment. This includes developing innovative techniques for assessing eye health at home and in the community, as well as in a hospital setting. We also aim to ensure vulnerable groups are not excluded, which means streamlining and developing access to eye care in a way that is fair for everyone.
We aim to build on our world-leading collections of digital data that include imaging, health records and genetics. By combining these with clinical data and basic science knowledge, and applying AI, we will gain insights into the causes of eye diseases and learn how best to prevent and treat them. Ultimately, this will allow us to tailor interventions to suit specific populations and individuals.
We aim to continue researching and discovering the normal and abnormal functioning of the eye, at a molecular, cellular and tissue level. This includes the processes of blood vessels, inflammation and the nervous system. Disturbances in these systems underlie most causes of sight loss and general diseases; greater understanding of them will lead to better diagnosis and treatment.
To continue our previous success in discovery and development of new, improved types of treatment by innovating with gene and stem-cell therapy, antibodies, laser, small molecules and novel micro-devices. Some of these regenerate ageing or damaged tissues, including stem cells. Some take only minutes to administer, and are specifically designed to treat some common eye conditions in a single treatment, with benefits lasting years.
Our Partnership
Moorfields Eye Hospital NHS Foundation Trust is a world-leading provider of eye care services in the UK, with patients in over 30 locations in and around London. It also operates commercial divisions that provide care to private patients, both in London and the Middle East. With its academic partner, the UCL Institute of Ophthalmology, Moorfields Eye Hospital is recognised as a world-leading centre of excellence in eye research and education.
The UCL Institute of Ophthalmology (IoO) is one of a number of specialist biomedical research centres within UCL. It conducts cutting-edge science and attracts researchers of the highest international calibre. The outstanding quality of research carried out at the IoO was confirmed by the most recent HEFCE (Higher Education Funding Council for England) Research Evaluation Framework exercise. UCL IoO was also ranked as the best place in the world to study ophthalmology in the 2017 Centre for World University Rankings.
Our partnership encompasses both infrastructure and education across Moorfields and UCL IoO, including the NIHR Clinical Research Facility: Moorfields (CRF).
About the NIHR (National Institute for Health and Care Research)
The NIHR Biomedical Research Centres (BRCs)
NIHR BRCs are collaborations between NHS organisations and universities. They bring together academics and clinicians to translate scientific discoveries into potential new treatments, diagnostics and technologies. In 2022, the NIHR awarded £816 million over five years to 20 BRCs across England, including the NIHR BRC: Moorfields.